MicroDISS 2-20ml mini Dissolution Tester from PION

The microDISS Profiler™ offers enhanced accuracy in small volume dissolution testing for various dosage forms including tablets, capsules, powders, and films. It enables intrinsic dissolution studies of miniaturized compressed pellets and supports biorelevant dissolution, excipient and salt screening, as well as dynamic media composition changes. The system is ideal for monitoring polymorphic transitions and precipitation patterns, and for determining both intrinsic and kinetic solubility in aqueous and non-aqueous media. Additionally, it facilitates solution stability testing of drug candidates, nanoparticle dissolution profiling, supersaturation behavior studies, and the impact of micro- and nanonization on dissolution performance.

The in situ fiber optic UV monitoring system is designed for real-time concentration measurement in small volumes ranging from 2 to 20 mL. Powered by AuPRO™, the most comprehensive dissolution data analysis software in the industry, it allows users to evaluate solubility, intrinsic disc dissolution rate, dissolution profiles, supersaturation, and precipitation patterns with high precision. Featuring a user-friendly graphical interface, the system enables simultaneous real-time data collection and analysis, providing efficient and accurate insights into complex dissolution behaviors.